Postsynthesis vapor-phase functionalization of MCM-48 with hexamethyldisilazane and 3-aminopropyldimethylethoxylsilane for bioseparation applications

Abstract

MCM-48 was surface modified via vapor-phase reactions with hexamethyldisilazane (CH3-MCM-48) and 3- aminopropyldimethylethoxysilane (NH2-MCM-48). 29Si NMR confirmed that the resulting materials contained covalently attached trimethylsilane and 3-aminopropyldimethylsilane moieties, both important functionalities for bioseparation applications. The surface coverage was ∼1.8 and 0.9 groups per nm2, respectively. The X-ray diffraction patterns and the narrow pore size distributions obtained from the gas sorption isotherms showed that the modified materials retained the characteristic pore structure of the underlying MCM-48 material. CH3-MCM-48 exhibited significantly improved hydrolytic stabilit..